Roadmap Epigenomics Project

Program Initiatives

Reference Epigenome Mapping Centers

This initiative is being issued as a cooperative agreement (U01) to support reference epigenome production centers that will develop reference epigenomes of a variety of human cells.

Epigenomics Data Analysis and Coordination Center (EDAAC)

This cooperative agreement (U01) will fund the Epigenomics Data Analysis and Coordination Center (EDACC), which will provide data analysis and coordination for all of the Reference Epigenome Mapping Centers.

Technology Development in Epigenomics

This initiative will support technology development in two important areas of epigenetics research.

Discovery of Novel Epigenetic Marks in Mammalian Cells

This initiative will support research to identify stable, long term changes in epigenetic processes and establish the utility of these marks in mammalian cells. More Epigenomics of Human Health and Disease

Epigenomics of Human Health and Disease

This initiative will support research on fundamental epigenomic changes or mechanisms underlying specific diseases; conditions of development or aging; or response to exposures (physical, chemical, behavioral, and social factors). This initiative will be funded as a 50/50 cost share between the NIH Roadmap and specific NIH Institutes, Centers, and Offices. The initiative will be released under multiple funding mechanisms dependent on research priorities and needs of participating ICs. The Roadmap/IC co-funding mechanism will foster multiple IC involvement and ensure easy transition to individual ICs at the end of each funding period. The first set of RFAs are expected to be released in 2008, with additional RFAs released annually beginning in 2009.

RFA-ES-10-002
- Opening Date: August 29, 2010
- Application Due Date: September 29, 2010